Eligible infants: 28 weeks of gestation or less
This is a masked randomized clinical trial in which extremely preterm infants fed human milk are randomly assigned to receive either a protein-enriched diet (intervention group) or a usual diet (control group) within the first 96 hours after birth
Eligible infants: 28 weeks of gestation or less
This clinical trial aims to investigate the effects of different vitamin D doses on extremely preterm infants who are fed human milk. A total of 126 infants will be enrolled and randomly assigned to either the intervention group, which will receive the highest recommended vitamin D dose, or the control group, which will receive the lowest recommended dose, during the first 14 days after birth. The main outcomes that will be assessed are the severity of respiratory morbidity, measured by a scoring system based on ventilatory support and oxygen supplementation, and pulmonary mechanics, measured using a non-invasive oscillometry device. Specifically, the area under the reactance curve (AX) will be determined using the tremoflo N-100 Neo Oscillometry device.
Eligible infants: 28 to 32 weeks of gestation
This is an unmasked randomized clinical trial in which very preterm infants fed human milk are randomly assigned to receive either exclusive enteral nutrition with minimal parenteral nutrition (intervention group) or usual parenteral nutrition with minimal enteral nutrition (control group) within the first 48 hours after birth
Eligible infants: 29 to 33 weeks of gestation
This is an unmasked randomized clinical trial in which 80 infants born very preterm receiving early and exclusive enteral nutrition will be assigned to one of two groups. Half of the infants will receive early fortification, starting between day 4 and 7 after birth, while the other half will receive delayed fortification, starting between day 10 and 14. The goal is to investigate whether providing early protein supplementation through early fortification in infants receiving early and exclusive enteral nutrition leads to higher lean mass accretion and greater diversity in the gut microbiome.
Eligible infants: 32 weeks of gestation or less
This is a prospective cohort study of human milk diets during the early postnatal development of premature babies. We want to look closely at the amounts of protein that infants receive during the first month of life to determine how it affects lean body mass accretion.
We recently examined the effects of early progression of feeding volumes on fluid balance and neurodevelopment in infants born extremely preterm. The research involved 60 infants who were randomly assigned to either an early feeding group (receiving 1 day of trophic feeding volumes) or a late feeding group (receiving 4 days of trophic feeding volumes at a rate of 20-24 mL/kg/day).
We recently reported that higher enteral protein intake in extremely preterm infants fed fortified human milk increases fat-free mass accretion and promotes growth without causing excessive body fat accretion.
We recently reported that higher enteral protein intake in extremely preterm infants fed fortified human milk increases fat-free mass accretion and promotes growth without causing excessive body fat accretion.
In this secondary analysis of the Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT), we evaluated the effects of early treatment with CPAP on nutritional intake and in-hospital growth rates of extremely preterm infants.
We determined that there is a strong association between postnatal growth alterations defined by the INTEGROWTH-21st growth curves and adverse cognitive outcomes at 2 years of age.
After measuring body fat by air-displacement plethysmography in preterm infants randomized to receive either high-volume (180-200 mL/kg/day) or usual volume feeding (140-160 mL/kg/day), we concluded that there are no significant differences in the amount of body fat between infants receiving high or usual-volume feeds.
Copyright © 2022 Neonatal Nutrition Research - All Rights Reserved.
This website is independently owned
We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.